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Severe underweight decreases the survival rate in adult lung transplantation

Komatsu, Teruya; Chen-Yoshikawa, Toyofumi F.; Oshima, Ayako; Harashima, Shin-Ichi; Aoyama, Akihiro; Inagaki, Nobuya; Date, Hiroshi

Oct 1, 2017

Surgery Today. 2017. 47(10): 1243-1248.

Abstract
Purpose: The body mass index (BMI) before lung transplantation (LT) is a benchmark of the post-LT survival. The aim of the study is to determine the BMI inadequate for the post-LT survival.

Methods: We examined the survival after LT in patients grouped into the following BMI categories: <18.5 kg/m2 (underweight), 18.5-24.9 kg/m2 (normal weight), 25-29.9 kg/m2 (overweight), and ≥30.0 kg/m2 (obese) according to the World Health Organization (WHO) criteria. A more detailed categorization was made for further evaluation of the underweight group: mild (17.0 ≤ BMI < 18.5 kg/m2) and severely underweight (BMI <17.0 kg/m2).

Results: There was no statistically significant difference in the post-LT survival between underweight and normal-weight patients (5-year survival: 78.7 vs. 76.1%). Patients with BMI <17.0 kg/m2 had a worse prognosis than those with 17.0 ≤ BMI < 18.5 kg/m2 (5-year survival: 70.3 vs. 90.0%).

Conclusions: Standard BMI categorization per the WHO criteria is inadequate for determining the post-LT survival, especially in underweight patients. For the nutritional evaluation of underweight pre-LT patients, BMI <17.0 kg/m2 should be used instead of BMI <18.5 kg/m2.

References
1. Acta Chir Belg. 2015 Sep-Oct;115(5):341-7
2. N Engl J Med. 1986 May 1;314(18):1140-5
3. Interact Cardiovasc Thorac Surg. 2015 Jul;21(1):28-33
4. Biol Blood Marrow Transplant. 2014 Aug;20(8):1169-75
5. J Heart Lung Transplant. 2001 Mar;20(3):288-96
6. Transplant Proc. 2010 Oct;42(8):3026-8
7. Am J Respir Crit Care Med. 2011 Nov 1;184(9):1055-61
8. Am J Transplant. 2015 Aug;15(8):2188-96
9. Proc Nutr Soc. 2015 Nov;74(4):337-47
10. World Health Organ Tech Rep Ser. 2000;894:i-xii, 1-253
11. J Heart Lung Transplant. 2015 Jan;34(1):1-15
12. J Heart Lung Transplant. 2005 Feb;24(2):137-44
13. Ann Thorac Surg. 2006 May;81(5):1844-9; discussion 1849-50
14. JPEN J Parenter Enteral Nutr. 2013 Jan;37(1):37-43
15. Am J Respir Crit Care Med. 2014 Nov 1;190(9):1012-21
16. J Heart Lung Transplant. 2010 Sep;29(9):1026-33
17. Curr Opin Organ Transplant. 2015 Oct;20(5):515-20
18. Chest. 2005 Jan;127(1):161-5
19. J Heart Lung Transplant. 2013 Jul;32(7):693-700
20. Clin Transplant. 2009 Nov-Dec;23(6):819-30
21. Transplant Proc. 2014 Jun;46(5):1506-10
22. Surg Today. 2015 Oct;45(10):1271-9
23. Am J Transplant. 2009 Feb;9(2):389-96
24. J Bras Pneumol. 2009 Mar;35(3):242-7
25. Gen Thorac Cardiovasc Surg. 2016 Feb;64(2):93-7
26. Surg Today. 2016 Dec;46(12 ):1415-1419
27. Chest. 1998 Jul;114(1):51-60
28. N Engl J Med. 2004 Dec 23;351(26):2761-6
29. Interact Cardiovasc Thorac Surg. 2016 Mar;22(3):314-20

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BMI, Transplant

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